The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 17, 2014

Filed:

Oct. 05, 2012
Applicants:

David A. Claremon, Maple Glen, PA (US);

Frank Himmelsbach, Mittelbiberach, DE;

Katerina Leftheris, San Diego, CA (US);

Suresh B. Singh, Kendall Park, NJ (US);

Colin M. Tice, Ambler, PA (US);

Zhenrong Xu, Chalfont, PA (US);

Yuanjie YE, Ambler, PA (US);

Linghang Zhuang, Chalfont, PA (US);

Inventors:

David A. Claremon, Maple Glen, PA (US);

Frank Himmelsbach, Mittelbiberach, DE;

Katerina Leftheris, San Diego, CA (US);

Suresh B. Singh, Kendall Park, NJ (US);

Colin M. Tice, Ambler, PA (US);

Zhenrong Xu, Chalfont, PA (US);

Yuanjie Ye, Ambler, PA (US);

Linghang Zhuang, Chalfont, PA (US);

Assignees:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 413/10 (2006.01); C07D 413/14 (2006.01); A61K 31/5355 (2006.01);
U.S. Cl.
CPC ...
Abstract

Disclosed is a compound represented by Formula (Im): or a pharmaceutically acceptable salt, monohydrate, enantiomer or diastereomer thereof. Also disclosed are pharmaceutical compositions comprising the compound of Formula (Im) or a pharmaceutically acceptable salt, monohydrate, enantiomer or diastereomer thereof and methods of inhibiting 11β-HSD1 activity comprising the step of administering to a mammal in need of such treatment an effective amount of a compound of Formula (Im), or a pharmaceutically acceptable salt, monohydrate, enantiomer or diastereomer thereof. Values for the variables in Formula (Im) are defined herein.


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