The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 17, 2014
Filed:
May. 02, 2011
John E. Thompson, Waterloo, CA;
Bruce C. Galton, Madison, NJ (US);
Catherine Taylor, Waterloo, CA;
Charles Dinarello, Boulder, CO (US);
Leonid Reznikov, Aurora, CO (US);
Adrienne Boone, Waterloo, CA;
Marianne Hopkins, New Hamburg, CA;
John E. Thompson, Waterloo, CA;
Bruce C. Galton, Madison, NJ (US);
Catherine Taylor, Waterloo, CA;
Charles Dinarello, Boulder, CO (US);
Leonid Reznikov, Aurora, CO (US);
Adrienne Boone, Waterloo, CA;
Marianne Hopkins, New Hamburg, CA;
Senesco Technologies, Inc., New Brunswick, NJ (US);
Abstract
The present invention relates to apoptosis specific eucaryotic initiation factor 5A (eIF-5A), referred to as apoptosis-specific eIF-5A or eIF5A1, nucleic acids and polypeptides and methods for inhibiting or suppressing apoptosis in cells using antisense nucleotides or siRNAs to inhibit expression of apoptosis-specific eIF-5A. The invention also relates to suppressing or inhibiting expression of pro-inflammatory cytokines or inhibiting activation of NFkB by inhibiting expression of apoptosis-specific eIF-5A.