The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 17, 2014

Filed:

Sep. 05, 2008
Applicants:

Paul G. Allen, Seattle, WA (US);

Edward S. Boyden, Cambridge, MA (US);

Roderick A. Hyde, Redmond, WA (US);

Muriel Y. Ishikawa, Livermore, CA (US);

Stephen L. Malaska, Redmond, WA (US);

Dennis J. Rivet, Portsmouth, VA (US);

Leif T. Stordal, Issaquah, WA (US);

Lowell L. Wood, Jr., Bellevue, WA (US);

Inventors:

Paul G. Allen, Seattle, WA (US);

Edward S. Boyden, Cambridge, MA (US);

Roderick A. Hyde, Redmond, WA (US);

Muriel Y. Ishikawa, Livermore, CA (US);

Stephen L. Malaska, Redmond, WA (US);

Dennis J. Rivet, Portsmouth, VA (US);

Leif T. Stordal, Issaquah, WA (US);

Lowell L. Wood, Jr., Bellevue, WA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); C07H 21/02 (2006.01); C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

Methods, pharmaceutical compositions, and kits are provided which includes accurately sampling a RNA from a tissue of an animal and analyzing RNA in the tissue of the animal as an indicator of physiological state, infectious disease, neoplastic disease, autoimmune disease, inflammatory disease, cardiovascular disease, atherosclerotic disease, or neurological disease in the animal. A method is provided which includes administering at least one compound to an animal wherein the at least one compound is configured to prevent the cleavage of at least one tissue RNA by a ribonuclease. The method further includes collecting a sample of at least a portion of tissue from the animal.


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