The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 17, 2014
Filed:
Aug. 08, 2008
Applicants:
Wolfgang Fraunhofer, Newton, MA (US);
David W. Borhani, Hartsdale, NY (US);
Gerhard Winter, Penzberg, DE;
Stefan Gottschalk, Grunwald, DE;
Inventors:
Wolfgang Fraunhofer, Newton, MA (US);
David W. Borhani, Hartsdale, NY (US);
Gerhard Winter, Penzberg, DE;
Stefan Gottschalk, Grunwald, DE;
Assignee:
Abbvie Inc., North Chicago, IL (US);
Primary Examiner:
Int. Cl.
CPC ...
C12P 21/06 (2006.01); A61K 39/395 (2006.01); A01N 61/00 (2006.01); C07K 16/24 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/241 (2013.01); A61K 2039/505 (2013.01); C07K 2299/00 (2013.01); C07K 2316/96 (2013.01);
Abstract
The present invention relates to a batch crystallization method for crystallizing anti-human TNFalpha (hTNFalpha) antibody and antibody fragments which allows the production of said antibody on an industrial scale; a method of controlling the size of antibody crystals, for example, crystals of anti-hTNFalpha antibody fragments, compositions containing said crystals as well as methods of use of said crystals and compositions.