The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 17, 2014
Filed:
May. 23, 2006
Jun-jen Liu, Taipei, TW;
Chi-chun Lai, Taipei, TW;
Yun-long Tseng, Taipei, TW;
Luke S. S. Guo, South San Francisco, CA (US);
Keelung Hong, South San Francisco, CA (US);
Jun-Jen Liu, Taipei, TW;
Chi-Chun Lai, Taipei, TW;
Yun-Long Tseng, Taipei, TW;
Luke S. S. Guo, South San Francisco, CA (US);
Keelung Hong, South San Francisco, CA (US);
Taiwan Liposome Co. Ltd., Nankang, Taipei, TW;
TLC Biopharmaceuticals, Inc., South San Francisco, CA (US);
Abstract
The invention provides a liposome composition for delivering high pay-load of a therapeutic agent to neovascularization sites of the eyes in a patient in need thereof. The liposome composition for entrapping the therapeutic agent comprises a particle forming component composed of a variety of vesicle-forming lipids, and an agent-carrying component able to form a complex with the therapeutic agent via electrostatic charge-charge interaction or hydrophobic-hydrophobic interaction; wherein the liposome composition comprising the therapeutic agent has a mean particle diameter of about 30 to 200 nm and may accumulate at the neovascularization sites of the eyes 24 hours after the intravenous administration of the liposome composition comprising the therapeutic agent to the patient. A method for delivering the therapeutic agent to the eyes in a patient with this liposome composition is also provided.