The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 17, 2014
Filed:
Sep. 28, 2007
Shinobu Abe, Tokyo, JP;
Bunsichi Simizu, Tokyo, JP;
Shinobu Abe, Tokyo, JP;
Bunsichi Simizu, Tokyo, JP;
Japan Poliomyelitis Research Institute, Tokyo, JP;
Takeda Pharmaceutical Company Limited, Osaka, JP;
Abstract
The invention provides a process for producing a combined vaccine containing an inactivated Sabin strain of poliovirus, aprotective antigen, a diphtheria toxoid and a tetanus toxoid, the process including a step of producing a high-titer Sabin strain poliovirus. The inventive process for producing a combined vaccine, including a step of culturing, in the presence of from about 4 g/L to about 6 g/L of a microcarrier, Vero cells to be inoculated with a Sabin strain of poliovirus, is useful as a process for efficiently producing a combined vaccine containing an inactivated Sabin strain of poliovirus.