The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 10, 2014
Filed:
Feb. 05, 2010
Applicants:
Lung-hu Wang, Kaohsiung, TW;
Chun-teng Huang, Jiali Township, Tainan County, TW;
Inventors:
Lung-Hu Wang, Kaohsiung, TW;
Chun-Teng Huang, Jiali Township, Tainan County, TW;
Assignee:
Scinopharm Taiwan, Ltd., Tainan, TW;
Primary Examiner:
Int. Cl.
CPC ...
C07H 1/00 (2006.01); C07H 3/00 (2006.01); C08B 37/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
A process for the preparation of topiramate in an one pot reaction comprises the following steps: A) reacting 2,3:4,5-bis-O-{1-methylethylidene)-β-D-fructopyranose with sulfurylchloride in xylene in the presence of an organic or inorganic base to form 2,3:4,5-bis-O-(1-methylethylidene)-β-D-fructopyranose sulfuryl chloride, B) adding a second organic solvent to the mixture obtained in step A) C) reacting the mixture obtained in step B) with ammonia to form topiramate.