The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 10, 2014
Filed:
Jun. 08, 2011
Applicants:
Henry Wolfe, Glenmoore, PA (US);
Reinhard Ebner, Gaithersburg, MD (US);
Inventors:
Henry Wolfe, Glenmoore, PA (US);
Reinhard Ebner, Gaithersburg, MD (US);
Assignee:
Combimab, Inc., Chevy Chase, MD (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/04 (2006.01); C07K 7/08 (2006.01); C07K 7/00 (2006.01); C07K 1/107 (2006.01); C07K 1/00 (2006.01); A61K 38/10 (2006.01); A61K 38/00 (2006.01); A61P 1/10 (2006.01);
U.S. Cl.
CPC ...
Abstract
Therapeutic peptides having guanylyl cyclase C agonist activity are disclosed. The therapeutic peptides are analogues of theSTa peptide with non-natural amino acid, isosteric or D-amino acid substituents. The therapeutic peptides are useful in the treatment of chronic ideopathic constipation, inflammatory bowel disease, and other diseases. Pharmaceutical compositions comprising the therapeutic peptides are also disclosed.