logo

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8748485 B1

PDFFull Text
Expired
Date of Patent:
Jun. 10, 2014

Filed:

Dec. 01, 2011

Compound and medical use thereof

Applicants:

Masaya Kokubo, Osaka, JP;

Koji Yano, Osaka, JP;

Inventors:

Masaya Kokubo, Osaka, JP;

Koji Yano, Osaka, JP;

Assignee:

Ono Pharmaceuticals Co., Ltd., Osaka, JP;

Attorney:

Millen, White, Zelano & Branigan, P.C.

Primary Examiner:

Jeffrey S Lundgren

Assistant Examiner:

William Lee

Int. Cl.
CPC ...
A01N 37/34 (2006.01); A61K 31/275 (2006.01); A01N 37/12 (2006.01); A01N 37/44 (2006.01); A61K 31/195 (2006.01); C07C 229/00 (2006.01); A61K 31/198 (2006.01); C07C 229/36 (2006.01);
U.S. Cl.
CPC ...
A61K 31/198 (2013.01); C07C 229/36 (2013.01);
Abstract

Provided is a levodopa prodrug that overcomes the problems attributed to the blood kinetics of levodopa such as large number of doses and the incidence of side effects due to frequent dosing. (2S)-2-Amino-3-(3,4-bis((2-(benzoyloxy)-2-methylpropanoyl)oxy)phenyl)propanoic acid, a salt thereof, or a solvate thereof is a levodopa prodrug, and provides a flat blood concentration-time profile of levodopa through oral administration, and therefore is useful as a preventive and/or therapeutic agent for Parkinson's disease and/or Parkinson's syndrome that overcomes the problems associated with pharmaceutical preparations of levodopa.

Find Patent Forward Citations

Kokubo, Masaya. (2014). Compound and medical use thereof (U.S. Patent No. 8748485). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8748485

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

Loading…