The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 10, 2014

Filed:

Jul. 17, 2012
Applicants:

Alan P. Kozikowski, Chicago, IL (US);

Anatoly Dritschilo, Bethesda, MD (US);

Mira Jung, Rockville, MD (US);

Pavel A. Petukhov, Naperville, IL (US);

Bin Chen, Chicago, IL (US);

Inventors:

Alan P. Kozikowski, Chicago, IL (US);

Anatoly Dritschilo, Bethesda, MD (US);

Mira Jung, Rockville, MD (US);

Pavel A. Petukhov, Naperville, IL (US);

Bin Chen, Chicago, IL (US);

Assignee:

Georgetown University, Washington, DC (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/16 (2006.01); C07D 277/02 (2006.01); C07D 263/02 (2006.01); C07C 233/08 (2006.01); C07C 233/14 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention provides novel classes of HDAC inhibitors. Methods of sensitizing a cancer cell to the cytotoxic effects of radiotherapy are also provided as well as methods for treating cancer and methods for treating neurological diseases. Additionally, the invention further provides pharmaceutical compositions comprising an HDAC inhibitor of the invention, and kits comprising a container containing an HDAC inhibitor of the invention.


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