The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 10, 2014

Filed:

Mar. 03, 2012
Applicants:

Gary W. Jones, Newcastle, WA (US);

Anatoliy L. Tatarets, Kharkiv, UA;

Leonid D. Patsenker, Kharkiv, UA;

Inventors:

Gary W. Jones, Newcastle, WA (US);

Anatoliy L. Tatarets, Kharkiv, UA;

Leonid D. Patsenker, Kharkiv, UA;

Assignee:

Nanoquantum Sciences, Inc., Bellevue, WA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/438 (2006.01); A61K 31/404 (2006.01); A61K 31/403 (2006.01); A61N 5/10 (2006.01); C07D 401/02 (2006.01); C07D 209/58 (2006.01); C07D 209/04 (2006.01);
U.S. Cl.
CPC ...
A61K 31/438 (2013.01); A61K 31/404 (2013.01); A61K 31/403 (2013.01); A61N 5/10 (2013.01); C07D 401/02 (2013.01); C07D 209/58 (2013.01); C07D 209/04 (2013.01);
Abstract

Halo-organic heterocyclic compounds are described, which have the formulas Ring A is an aromatic ring bound to at least two halogen atoms, at least one of which is iodine or bromine. Also described are polymethine dyes based on these heterocyclic compounds, and dendrimeric compounds and conjugates of such polymethine dyes. The polymethine dyes are characterized by enhanced properties, e.g., brightness, photostability, sensitivity and/or selective affinity that make them useful to target cancer cells, pathogenic microorganisms, and/or other biological materials, in applications such as photodynamic therapy, photodynamic antimicrobial chemotherapy (PACT), cancer treatment, selective removal or attachment of biological materials, antimicrobial coating materials, and other diagnostic, theranostic, spectrum shifting, deposition/growth, and analytic applications.


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