The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 10, 2014

Filed:

Apr. 04, 2012
Applicants:

Guanglin Luo, Madison, CT (US);

Gene M. Dubowchik, Middlefleid, CT (US);

John E. Macor, Guilford, CT (US);

Ling Chen, Middletown, CT (US);

Inventors:

Guanglin Luo, Madison, CT (US);

Gene M. Dubowchik, Middlefleid, CT (US);

John E. Macor, Guilford, CT (US);

Ling Chen, Middletown, CT (US);

Assignee:

Bristol-Myers Squibb Company, Princeton, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/495 (2006.01); A01N 43/50 (2006.01); A01N 43/54 (2006.01); A01N 43/56 (2006.01); A01N 43/58 (2006.01);
U.S. Cl.
CPC ...
Abstract

The disclosure generally relates to the novel compounds of formula I, including pharmaceutically acceptable salts, which are CGRP receptor antagonists. The disclosure also relates to pharmaceutical compositions and methods for using the compounds in the treatment of CGRP related disorders including migraine and other headaches, neurogenic vasodilation, neurogenic inflammation, thermal injury, circulatory shock, flushing associated with menopause, airway inflammatory diseases such as asthma, and chronic obstructive pulmonary disease (COPD).


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