The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 10, 2014
Filed:
Dec. 20, 2011
Clifford Riley King, Hendersonville, NC (US);
Stephen G. D'ambrosio, Etowah, NC (US);
David W. Bristol, Mills River, NC (US);
Michael L. English, Cashiers, NC (US);
Clifford Riley King, Hendersonville, NC (US);
Stephen G. D'Ambrosio, Etowah, NC (US);
David W. Bristol, Mills River, NC (US);
Michael L. English, Cashiers, NC (US);
Pisgah Laboratories, Inc., Pisgah Forest, NC (US);
Abstract
A drug substance with a pharmaceutically acceptable organic acid addition salt of an opioid wherein said organic acid is selected from Structure A: wherein R-Rare independently selected from H, alkyl or substituted alkyl of 1-6 carbons, adjacent groups may be taken together to form a cyclic alkyl, cyclic alkyl-aryl, or cyclic aryl moiety;Ris selected from H, or an alkali earth cation;Rand Rare independently selected from H, alkyl of 1-6 carbons, an alkali earth cation, and aryl of 6 to 12 carbons, in a number sufficient to complete the valence bonding of X, andwherein X is selected from nitrogen, oxygen or sulfur; andwherein the drug substance has a morphology selected from amorphous and crystalline.