The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 10, 2014
Filed:
Mar. 30, 2011
Freda Miller, Toronto, CA;
David Kaplan, Toronto, CA;
Kristen Smith, San Clemente, CA (US);
Maryline Paris, Toronto, CA;
Sibel Naska, Toronto, CA;
Freda Miller, Toronto, CA;
David Kaplan, Toronto, CA;
Kristen Smith, San Clemente, CA (US);
Maryline Paris, Toronto, CA;
Sibel Naska, Toronto, CA;
The Hospital for Sick Children, Toronto, CA;
Abstract
We have discovered that p63 inhibition results in increased cellular proliferation. We have also performed a screen for agents capable of increasing cellular proliferation, (e.g., of stem cells such as skin-derived precursors (SKPs)). The invention therefore invention provides compositions, methods, and kits for increasing proliferation of cells, using compounds that decrease p63 expression or activity or using the compounds described herein. The invention also features methods of using these compounds for increasing hair growth, improving skin health, or promoting skin repair in a subject.