The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 10, 2014
Filed:
Oct. 21, 2009
Hiroshi Nakatake, Kikuchi, JP;
Akihiro Meta, Kikuchi, JP;
Kiyotaka Suenaga, Kikuchi, JP;
Masaki Hirashima, Kikuchi, JP;
Hiroaki Maeda, Kikuchi, JP;
Hiroshi Nakatake, Kikuchi, JP;
Akihiro Meta, Kikuchi, JP;
Kiyotaka Suenaga, Kikuchi, JP;
Masaki Hirashima, Kikuchi, JP;
Hiroaki Maeda, Kikuchi, JP;
The Chemo-Sero-Therapeutic Research Institute, Kumamoto-shi, JP;
Teijin Pharma Limited, Tokyo-to, JP;
Abstract
A process for preparing an inclusion body-forming protein is provided. A nucleic acid fragment having a nucleotide sequence coding for a modified alkaline phosphatase signal peptide (modified APSP) where leucine at the 13th position in the amino acid sequence shown in SEQ ID NO: 1 is substituted with proline and/or alanine at the 21st position is substituted with the other amino acid, downstream of which nucleotide sequence is bound a nucleotide sequence of a gene of a protein of interest is also provided.