The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 10, 2014

Filed:

Jun. 07, 2011
Applicants:

Louis M. Staudt, Silver Spring, MD (US);

Andreas Rosenwald, Bethesda, MD (US);

Wyndham Wilson, Washington, DC (US);

Todd S. Barry, Seattle, WA (US);

Adrian Wiestner, Bethesda, MD (US);

Inventors:

Louis M. Staudt, Silver Spring, MD (US);

Andreas Rosenwald, Bethesda, MD (US);

Wyndham Wilson, Washington, DC (US);

Todd S. Barry, Seattle, WA (US);

Adrian Wiestner, Bethesda, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/574 (2006.01);
U.S. Cl.
CPC ...
Abstract

It has been surprisingly found that ZAP-70 expression, both at the protein and mRNA levels, is indicative of clinical subgroups of CLL/SLL patients. In particular, high ZAP-70 expression is indicative of Ig-unmutated CLL/SLL. Methods are provided for discriminating between clinical subgroups of CLL/SLL, by determining whether subjects overexpress ZAP-70 mRNA or protein.


Find Patent Forward Citations

Staudt, Louis. (2014). Zap-70 expression as a marker for chronic lymphocytic leukemia / small lymphocytic lymphoma (cll/sll) (U.S. Patent No. 8748114). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8748114

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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