The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 10, 2014

Filed:

Dec. 06, 2011
Applicants:

Evelyn M. Mckeegan, Lake Forest, IL (US);

Barry L. Dowell, Mundelein, IL (US);

Richard R. Lesniewski, Collegeville, PA (US);

Dimitrí Semizarov, Chicago, IL (US);

Inventors:

Evelyn M. McKeegan, Lake Forest, IL (US);

Barry L. Dowell, Mundelein, IL (US);

Richard R. Lesniewski, Collegeville, PA (US);

Dimitrí Semizarov, Chicago, IL (US);

Assignee:

AbbVie Inc., North Chicago, IL (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/53 (2006.01); A01N 61/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Disclosed are methods for classifying a patient with cancer as a candidate for therapy with a Bcl-2 family inhibitor comprising determining the level of at least one biomarker in a sample and comparing the biomarker level to a threshold level. Also described are methods for identifying classes of patients having a refractory cancer for second-line therapy comprising a Bcl-2 family inhibitor, where the method comprises determining the level of at least one biomarker in a sample and comparing the biomarker level to a threshold level.


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