The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 10, 2014
Filed:
Aug. 30, 2007
Yuk Ming Dennis Lo, Hong Kong, CN;
Yu Kwan Tong, Hong Kong, CN;
Wai Kwun Rossa Chiu, Hong Kong, CN;
Chunming Ding, Hong Kong, CN;
Yuk Ming Dennis Lo, Hong Kong, CN;
Yu Kwan Tong, Hong Kong, CN;
Wai Kwun Rossa Chiu, Hong Kong, CN;
Chunming Ding, Hong Kong, CN;
The Chinese University of Hong Kong, Hong Kong, CN;
Abstract
Disclosed herein are methods and kits for selectively amplifying, detecting or quantifying a DNA fragment with a specific end sequence, especially generated following restriction enzyme digestion. This method can be used, for example, to detect a hypomethylated DNA fragment. This methods and kits are especially useful in detecting or quantifying a hypomethylated fetal DNA fragment in a maternal plasma sample containing a corresponding hypermethylated maternal DNA fragment.