The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 10, 2014

Filed:

Feb. 12, 2010
Applicants:

Jiang Zhang, Coppell, TX (US);

Colin J. Meyer, Southlake, TX (US);

Inventors:

Jiang Zhang, Coppell, TX (US);

Colin J. Meyer, Southlake, TX (US);

Assignee:

Reata Pharmaceuticals, Inc., Irving, TX (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/16 (2006.01); A61K 9/50 (2006.01);
U.S. Cl.
CPC ...
Abstract

Pharmaceutical formulations exhibit a desirably low Cmax, among other properties, that contain particles of amorphous bardoxolone methyl, either in pure form or in the form of a solid dispersion, admixed with particles of a hydrophilic binding agent. Such formulations possess the advantage of higher oral bioavailability, relative to formulations based on the crystalline form of bardoxolone methyl.


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