The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 10, 2014
Filed:
Jul. 05, 2012
Applicants:
Carrie M. Rosenberger, San Francisco, CA (US);
Alan A. Aderem, Seattle, WA (US);
Inventors:
Carrie M. Rosenberger, San Francisco, CA (US);
Alan A. Aderem, Seattle, WA (US);
Assignee:
Institute for Systems Biology, Seattle, WA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/12 (2006.01); C12N 7/00 (2006.01); C12N 7/02 (2006.01); C12N 7/04 (2006.01);
U.S. Cl.
CPC ...
Abstract
The invention is directed to an improved method to manufacture virus for use in vaccine by culturing infected cells that have been modified to overexpress miR-144. The invention is also directed to manipulating the activity or level of miR-144 in subjects in order to modulate the antiviral and immune response systems.