The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 10, 2014
Filed:
Oct. 31, 2007
Brett P. Giroir, Vienna, VA (US);
Monte S. Willis, Chapel Hill, NC (US);
Vidal F. DE LA Cruz, Jr., Phoenixville, PA (US);
Thais M. Sielecki-dzurdz, Kennett Square, PA (US);
Brett P. Giroir, Vienna, VA (US);
Monte S. Willis, Chapel Hill, NC (US);
Vidal F. De La Cruz, Jr., Phoenixville, PA (US);
Thais M. Sielecki-Dzurdz, Kennett Square, PA (US);
Baxter International, Inc., Deerfield, IL (US);
Baxter Healthcare SA, Glattpark, Opfikon, CH;
Board of Regents, The University of Texas System, Austin, TX (US);
Abstract
One embodiment of the present invention relates to a pharmaceutical composition, which includes a therapeutically effective amount of at least one anti-MIF antibody; and at least one pharmaceutically acceptable carrier. Another embodiment of the present invention relates to a pharmaceutical composition, which includes a therapeutically effective amount at least one anti-CD74 antibody; and at least one pharmaceutically acceptable carrier. Another embodiment of the present invention relates to a pharmaceutical composition, which includes a therapeutically effective amount of at least one anti-TNFR antibody; a therapeutically effective amount of at least one anti-MIF antibody; and at least one pharmaceutically acceptable carrier. Other embodiments of the present invention relate to methods of treating or preventing cardiac dysfunction, cardiodepression, burn injury-associated cardiac dysfunction, improving cardiac function in a subject following acute myocardial infarction, and identifying an MIF inhibitor.