The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 10, 2014
Filed:
Dec. 13, 2011
Ashfaq Mahmood, Newton Center, MA (US);
Alun G. Jones, Newton Center, MA (US);
Naengnoi Limpa-amara, Cambridge, MA (US);
Yijie Peng, Belmont, MA (US);
Zeynep Akgun, Boston, MA (US);
Ashfaq Mahmood, Newton Center, MA (US);
Alun G. Jones, Newton Center, MA (US);
Naengnoi Limpa-Amara, Cambridge, MA (US);
Yijie Peng, Belmont, MA (US);
Zeynep Akgun, Boston, MA (US);
President and Fellows of Harvard College, Cambridge, MA (US);
Abstract
The present invention relates to compounds and related technetium and rhenium complexes thereof which are suitable for imaging or therapeutic treatment of tissues, organs, or tumors. In another embodiment, the invention relates to methods of imaging tissues, organs, or tumors using radiolabeled metal complexes, particularly tissues, organs, or tumors which express certain receptors to which the compounds or complexes of the invention have an affinity. The present invention also relates to methods of treating cancer, particularly those cancer lines which express certain receptors to which the compounds or complexes of the invention have an affinity. In yet another embodiment, the present invention provides methods of imaging and/or inhibiting receptors or neuroreceptors using compounds or complexes of the invention which have an affinity for the receptor or neuroreceptor to be imaged and/or inhibited.