The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 03, 2014

Filed:

May. 12, 2011
Applicants:

Christopher J. Lesiak, Lincoln, NE (US);

Ahmed Bouzid, Lincoln, NE (US);

David Franzen, Lincoln, NE (US);

Inventors:

Christopher J. Lesiak, Lincoln, NE (US);

Ahmed Bouzid, Lincoln, NE (US);

David Franzen, Lincoln, NE (US);

Assignee:

LI-COR, Inc., Lincoln, NE (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
H04N 5/235 (2006.01);
U.S. Cl.
CPC ...
Abstract

Systems and methods are described for extending the dynamic range of imaging systems, and more particularly fluorescence or luminescence imaging systems, having low optical background and a linear detector response. Images of a sample at each of a set of exposure times are acquired, a system-level dark estimate for each exposure time is subtracted from each image to form dark-corrected images, and the different exposures (dark-corrected images) are merged into a wider dynamic-range image. Typically merging is performed on a pixel-by pixel basis.


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