The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 03, 2014
Filed:
Oct. 23, 2009
Peyman Najmabadi, Vista, CA (US);
Gregory J. Crandall, Vista, CA (US);
Aaron Alan Stearrett, Vista, CA (US);
Dirk G. Soenksen, Vista, CA (US);
Christopher Adam Lee, Vista, CA (US);
Cynthia Perz, Vista, CA (US);
Peyman Najmabadi, Vista, CA (US);
Gregory J. Crandall, Vista, CA (US);
Aaron Alan Stearrett, Vista, CA (US);
Dirk G. Soenksen, Vista, CA (US);
Christopher Adam Lee, Vista, CA (US);
Cynthia Perz, Vista, CA (US);
Leica Biosystems Imaging, Inc., Vista, CA (US);
Abstract
A whole slide fluorescence digital pathology system is provided that uses a monochrome TDI line scan camera, which is particularly useful in fluorescence scanning where the signal is typically much weaker than in brightfield microscopy. The system uses oblique brightfield illumination for fast and accurate tissue finding and employs a unique double sweep focus scoring and objective lens height averaging technique to identify focus points and create a focus map that can be followed during subsequent scanning to provide autofocusing capability. The system also scans and analyzes image data to determine the optimal line rate for the TDI line scan camera to use during subsequent scanning of the digital slide image and it also creates a light profile to compensate for loss of illumination light due to roll off.