The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 03, 2014
Filed:
Nov. 28, 2011
Mitsutoshi Setou, Hamamatsu, JP;
Shigeki Kajihara, Uji, JP;
Mitsutoshi Setou, Hamamatsu, JP;
Shigeki Kajihara, Uji, JP;
Shimadzu Corporation, Kyoto-Shi, JP;
Abstract
In an imaging mass analysis, image information of a sample allows users to grasp specific information about the sample, such as distribution of a portion with a particular function or effect. The mass spectrum intensity data are normalized for each pixel so that the sum of the intensities over the entire mass-to-charge ratio (m/z) is one. Entropy is calculated by totaling the product of the intensity normalizing at each m/z and the logarithm of that intensity over the entire m/z range. After the entropy is calculated for each pixel, the pixels are colored according to their entropy values to display a two-dimensional color image of entropy distribution. The entropy of a cancerous portion is relatively small because of a high content of a specific kind of substance and the simplified composition of the substances. Thus, the cancerous part and the normal part of the entropy image can be distinguished.