The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 03, 2014
Filed:
May. 06, 2010
Applicants:
Chris Meier, Jork, DE;
Viktoria Caroline Tonn, Hamburg, DE;
Inventors:
Chris Meier, Jork, DE;
Viktoria Caroline Tonn, Hamburg, DE;
Assignee:
Universitaet Hamburg, Hamburg, DE;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07H 19/04 (2006.01); C07H 19/20 (2006.01); C07G 3/00 (2006.01); C07H 17/00 (2006.01); C08B 37/00 (2006.01); C07H 5/04 (2006.01); C07H 5/06 (2006.01);
U.S. Cl.
CPC ...
Abstract
The invention relates to a method for producing phosphate-bridged nucleoside conjugates. In the method, a cyclosaligenyl nucleotide is produced first, to which a linker is added, which is used to perform the immobilization on a solid phase. A subsequent reaction with corresponding nucleophiles results in the desired phosphate-bridged nucleoside conjugates, which can then again be cleaved from the solid phase-bound linker.