The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 03, 2014
Filed:
Jun. 20, 2012
Lawrence M. Blatt, San Francisco, CA (US);
Scott D. Seiwert, Pacifica, CA (US);
Leonid Beigelman, San Mateo, CA (US);
Ramachandran Radhakrishnan, Fremont, CA (US);
Karl Kossen, Brisbane, CA (US);
Vladimir Serebryany, Burlingame, CA (US);
Lawrence M. Blatt, San Francisco, CA (US);
Scott D. Seiwert, Pacifica, CA (US);
Leonid Beigelman, San Mateo, CA (US);
Ramachandran Radhakrishnan, Fremont, CA (US);
Karl Kossen, Brisbane, CA (US);
Vladimir Serebryany, Burlingame, CA (US);
Intermune, Inc., Brisbane, CA (US);
Abstract
Disclosed are methods of modulating a stress activated protein kinase (SAPK) system with an active compound, wherein the active compound exhibits low potency for inhibition of at least one p38 MAPK; and wherein the contacting is conducted at a SAPK-modulating concentration that is at a low percentage inhibitory concentration for inhibition of the at least one p38 MAPK by the compound. Also disclosed are derivatives of pirfenidone. These derivatives can modulate a stress activated protein kinase (SAPK) system.