The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 03, 2014
Filed:
Jun. 08, 2012
Yoshiro Niitsu, Hokkaido, JP;
Victor Knopov, Oceanside, CA (US);
Joseph E. Payne, Oceanside, CA (US);
Richard P. Witte, San Diego, CA (US);
Mohammad Ahmadian, Carlsbad, CA (US);
Loren A. Perelman, Oakland, CA (US);
Violetta Akopian, Oceanside, CA (US);
Yasunobu Tanaka, Osaka, JP;
Elena Feinstein, Rehovot, IL;
Sharon Avkin-nahum, Nes Ziona, IL;
Hagar Kalinski, Rishon Le-Zion, IL;
Igor Mett, Rehovot, IL;
Kenjiro Minomi, Osaka, JP;
Wenbin Ying, San Diego, CA (US);
Yun Liu, San Diego, CA (US);
Yoshiro Niitsu, Hokkaido, JP;
Victor Knopov, Oceanside, CA (US);
Joseph E. Payne, Oceanside, CA (US);
Richard P. Witte, San Diego, CA (US);
Mohammad Ahmadian, Carlsbad, CA (US);
Loren A. Perelman, Oakland, CA (US);
Violetta Akopian, Oceanside, CA (US);
Yasunobu Tanaka, Osaka, JP;
Elena Feinstein, Rehovot, IL;
Sharon Avkin-Nahum, Nes Ziona, IL;
Hagar Kalinski, Rishon Le-Zion, IL;
Igor Mett, Rehovot, IL;
Kenjiro Minomi, Osaka, JP;
Wenbin Ying, San Diego, CA (US);
Yun Liu, San Diego, CA (US);
Nitto Denko Corporation, Osaka, JP;
Abstract
What is described are pharmaceutical compositions comprising a double-stranded nucleic acid molecule comprising a sense strand and an antisense strand wherein the sense and antisense strands are selected from the oligonucleotides described as SERPINH1_2 (SEQ ID NOS: 60 and 127), SERPINH1_45a (SEQ ID NOS: 98 and 165), and SERPINH1_51 (SEQ ID NOS: 101 and 168), and drug carrier comprising a mixture of a retinoid and a lipid vesicle, and methods of using these pharmaceutical compositions to treat a disease associated with hsp47 expression, including fibrosis.