The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 03, 2014
Filed:
May. 12, 2005
Geoffrey John Lindeman, Kew, AU;
Mark Shackleton, Ann Arbor, MI (US);
Francois Vaillant, Geelong West, AU;
Jane Ellen Visvader, Kew, AU;
Geoffrey John Lindeman, Kew, AU;
Mark Shackleton, Ann Arbor, MI (US);
Francois Vaillant, Geelong West, AU;
Jane Ellen Visvader, Kew, AU;
The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, AU;
Abstract
The present invention relates generally to a method for the generation of a substantially homogenous population of undifferentiated cells. More particularly, the present invention relates to a method for isolating a substantially homogenous population of stem cells, and in particular, mammary stem cells (MaSCs). The MaSCs of the present invention are isolated on the basis of differential levels of proteins present on their cell surface. The MaSCs of the present invention are particularly useful as targets for identifying agents which modulate MaSC survival, self-renewal, proliferation and/or differentiation in both normal and diseased tissue such as, but not limited to, tumor tissue, and, also as source of tissue for the regeneration, replacement and/or augmentation of tissue damaged and/or lost after disease or injury.