The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 03, 2014
Filed:
Jul. 15, 2009
Applicants:
Noboru Maki, Wako, JP;
Kenichi Mori, Wako, JP;
Hiromi Fukai, Wako, JP;
Inventors:
Assignee:
Advanced Life Science Institute, Inc., Wako-Shi, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/09 (2006.01); C12N 5/10 (2006.01); C12N 7/00 (2006.01); C07K 14/18 (2006.01);
U.S. Cl.
CPC ...
Abstract
An HCV/GBV-B chimeric virus which maintains the replication function of HCV and is capable of infecting tamarin is disclosed in order to construct an HCV animal model which can be used as a development or evaluation system for therapeutic agents for HCV. The HCV/GBV-B chimeric RNA comprises an RNA of hepatitis C virus and an RNA of GB virus-B, wherein the RNA of hepatitis C virus comprises an RNA encoding leucine at the 1804th position and lysine at the 1966th position in the amino acid sequence of the polyprotein of hepatitis C virus.