The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 03, 2014
Filed:
Sep. 14, 2012
Jamie Iain Campbell, Cambridgeshire, GB;
Duncan James Cochrane, Cambridgeshire, GB;
Donna Kirsty Finch, Cambridgeshire, GB;
Maria Anastasia Teresa Groves, Cambridge, GB;
David Christopher Lowe, Cambridge, GB;
Simon Charles Cruwys, Leicestershire, GB;
Jamie Iain Campbell, Cambridgeshire, GB;
Duncan James Cochrane, Cambridgeshire, GB;
Donna Kirsty Finch, Cambridgeshire, GB;
Maria Anastasia Teresa Groves, Cambridge, GB;
David Christopher Lowe, Cambridge, GB;
Simon Charles Cruwys, Leicestershire, GB;
Medimmune Limited, Cambridge, GB;
Abstract
This invention relates to binding members, especially antibody molecules, specific for interleukin 1 receptor 1 (IL-1R1). For example, isolated binding members specific for IL-1R1 which competes with IL-1 and IL-1Ra for binding to IL-1R1 and binds Il-1R1 with a Kof 10 pM or less when measured by Kinexa™. The binding members are useful for, inter alia, treatment of disorders mediated by IL-1R1 including rheumatoid arthritis, asthma and chronic obstructive pulmonary disease (COPD).