The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 03, 2014
Filed:
Nov. 19, 2012
Medical Diagnostic Laboratories, Llc, Hamilton, NJ (US);
David W. Hilbert, Burlington, NJ (US);
Scott E. Gygax, Yardely, PA (US);
Martin E. Adelson, East Windsor, NJ (US);
Eli Mordechai, Robbinsville, NJ (US);
Jessica Schuyler, Burlington, NJ (US);
Teresa Paulish-Miller, Yardley, PA (US);
Medical Diagnostic Laboratories, LLC, Hamilton, NJ (US);
Abstract
The present invention is directed to the discovery of single nucleotide polymorphisms (SNPs) in the presence of metronidazole-resistant. The presence of G76C, C213G, or C318A (SNP) in tvntr 4 or the presence of A238T, G427C, or T476C (SNP) in tvntr6 provides a reliable biomarker for the presence of metronidazole-resistant. The present invention further provides reagents used for detecting the SNPs to screen subjects for metronidazole resistance in