The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 03, 2014

Filed:

Sep. 07, 2007
Applicants:

Jason P. Hodde, West Lafayette, IN (US);

David M. J. Ernst, Indianapolis, IN (US);

Lal Ninan, Santa Rosa, CA (US);

Sherry Voytik-harbin, Zionsville, IN (US);

Nathan Hammond, Somerville, MA (US);

Inventors:

Jason P. Hodde, West Lafayette, IN (US);

David M. J. Ernst, Indianapolis, IN (US);

Lal Ninan, Santa Rosa, CA (US);

Sherry Voytik-Harbin, Zionsville, IN (US);

Nathan Hammond, Somerville, MA (US);

Assignee:

Cook Biotech Incorporated, West Lafayette, IN (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/12 (2006.01); A61L 27/36 (2006.01); A61L 27/22 (2006.01); A61K 35/38 (2006.01); A61K 38/18 (2006.01); A61K 35/37 (2006.01);
U.S. Cl.
CPC ...
A61K 35/37 (2013.01); A61L 27/3629 (2013.01); A61L 27/3633 (2013.01); A61L 27/3687 (2013.01); A61L 27/227 (2013.01); A61K 35/38 (2013.01); A61K 38/1825 (2013.01);
Abstract

Described are packaged, sterile medical graft products containing controlled levels of a growth factor such as Fibroblast Growth Factor-2 (FGF-2). Also described are methods of manufacturing medical graft products wherein processing, including sterilization, is controlled and monitored to provide medical graft products having modulated, known levels of a extracellular matrix factor, such as a growth factor, e.g. FGF-2. Preferred graft materials are extracellular matrix materials isolated from human or animal donors, particularly submucosa-containing extracellular matrix materials. Further described are ECM compositions that are or are useful for preparing gels, and related methods for preparation and use.


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