The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 03, 2014
Filed:
Aug. 13, 2012
Martin Folger, Ingelheim am Rhein, DE;
Stefan Lehner, Wiesbaden, DE;
Annette Grave, Loerrach, DE;
Norbert Poellinger, Muellheim, DE;
Randolph Seidler, Eckenroth, DE;
Martin Folger, Ingelheim am Rhein, DE;
Stefan Lehner, Wiesbaden, DE;
Annette Grave, Loerrach, DE;
Norbert Poellinger, Muellheim, DE;
Randolph Seidler, Eckenroth, DE;
Boehringer Ingelheim Vetmedica GmbH, Ingelheim am Rhein, DE;
Abstract
This application relates to taste masked multi-layered particles an inert core, one or more coating layer(s) comprising a pharmaceutically active ingredient and a binder, an intermediate coating layer (seal coating) free from a low molecular weight water-soluble ionic compound and comprising a water-soluble pharmaceutical film-forming compound selected from (i) HPMC and PEG or (ii) PVP, and an outer coating layer (final or taste masking coating) free from a low molecular weight water-soluble ionic compound and comprising (i) a poly(meth)acrylate or (ii) a mixture comprising 60-90% (w/w) EC and 10-40% (w/w) HPMC, wherein the pharmaceutically active ingredient is water-soluble and comprises either at least one basic group and/or a bitter taste. Further disclosed are methods for the production of such particles and pharmaceutical compositions comprising them.