The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 03, 2014

Filed:

Nov. 28, 2011
Applicants:

Abhijit Suresh Bhat, Encinitas, CA (US);

Curt William Bradshaw, San Diego, CA (US);

Olivier Alexandre Laurent, San Diego, CA (US);

Alice Lee, Poway, CA (US);

Richard Ryan Preston, Escondido, CA (US);

David Tumelty, San Diego, CA (US);

Lauren Diane Wood, San Diego, CA (US);

Wei Hong Yu, San Diego, CA (US);

Inventors:

Abhijit Suresh Bhat, Encinitas, CA (US);

Curt William Bradshaw, San Diego, CA (US);

Olivier Alexandre Laurent, San Diego, CA (US);

Alice Lee, Poway, CA (US);

Richard Ryan Preston, Escondido, CA (US);

David Tumelty, San Diego, CA (US);

Lauren Diane Wood, San Diego, CA (US);

Wei Hong Yu, San Diego, CA (US);

Assignee:

Covx Technologies Ireland, Limited, Dun Laoghaire County, Dublin, IE;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to Multifunctional Antibody Conjugates, comprising an antibody or antigen binding portion thereof, comprising at least a fragment of a light chain constant kappa region (CLκ) comprising Kaccording to Kabat numbering; a linker comprising the formula X-Y-Z, wherein Z is a group is covalently connected to the antibody through the side chain of K, Y is a linear or branched biologically compatible connecting chain, and X is a group covalently connected to at least one Effector Moiety. The invention further provides specific MAC compounds and compositions of the invention.


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