The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 03, 2014
Filed:
Oct. 19, 2010
Kenneth J. Dormer, Edmond, OK (US);
Sunny S. Po, Edmond, OK (US);
Benjamin J. Scherlag, Oklahoma City, OK (US);
Carey N. Pope, Stillwater, OK (US);
Kenneth J. Dormer, Edmond, OK (US);
Sunny S. Po, Edmond, OK (US);
Benjamin J. Scherlag, Oklahoma City, OK (US);
Carey N. Pope, Stillwater, OK (US);
The Board of Regents of the University of Oklahoma, Norman, OK (US);
Abstract
The present disclosure describes a method for targeted delivery of permanently-acting or temporarily-acting neurotoxins, neurosuppressants, or other compounds having a neurologic effect to specific locations of the heart, including for example, but not limited to, nodes of the cardiac autonomic nervous system such as the atrial ganglionated plexi (GP). Chemical ablation of the atrial GP as described herein via magnetically-targeted magnetically-susceptible nanoparticles can effectively suppress GP activity and atrial fibrillation related, thereto without permanent damage to either myocardium or intrinsic CANS.