The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 27, 2014
Filed:
Jun. 01, 2010
Applicants:
Carl A. Wesolowski, St. John's, CA;
Paul Babyn, Caledon, CA;
Richard Puetter, San Diego, CA (US);
Inventors:
Assignee:
Other;
Primary Examiner:
Int. Cl.
CPC ...
G06G 7/48 (2006.01); G01N 1/00 (2006.01); G06T 1/00 (2006.01);
U.S. Cl.
CPC ...
G01N 1/00 (2013.01); G06T 1/00 (2013.01);
Abstract
Plasma concentration of a compound of interest is measured in two or ideally 4 or more blood samples taken from a patient over a period of time following bolus injection. The measured values are input into a computer processor programmed to execute a computer program comprising an algorithm that uses the gamma variate (GV) function to model drug plasma concentration, then uses Tikhonov regularization to perform the fit, selecting a regularization constant so that the relative error in the plasma clearance is minimized. One or more output values representative of renal function are generated.