The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 27, 2014
Filed:
Aug. 18, 2010
Dharmaraj Ramachandra Rao, Maharashtra, IN;
Rajendra Narayanrao Kankan, Maharashtra, IN;
Sandip Vasant Chikhalikar, Maharashtra, IN;
Maruti Ghagare, Maharashtra, IN;
Dharmaraj Ramachandra Rao, Maharashtra, IN;
Rajendra Narayanrao Kankan, Maharashtra, IN;
Sandip Vasant Chikhalikar, Maharashtra, IN;
Maruti Ghagare, Maharashtra, IN;
Cipla Limited, Mumbai, IN;
Abstract
The present invention relates to a process for preparing naratriptan or a salt thereof, the process comprising: (a) reacting a compound of formula (3) with a compound of the formula HCCR wherein Z is a protecting group, Y is a leaving group and R is a trialkyl silyl group, a trialkylstannyl group or a zinc (II) halide, to obtain the compound of formula (4); (b) converting the compound of formula (4) to a compound of formula (5) wherein Z' is hydrogen or a benzyl group; (c) converting the compound of formula (5) to naratriptan; and (d) optionally converting naratriptan to a salt thereof. The present invention also provides novel compounds (3) and (4) and processes for their preparation.