The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 27, 2014
Filed:
Nov. 25, 2009
Amjad Ali, Freehold, NJ (US);
Joann M. Napolitano, North Plainfield, NJ (US);
Qiaolin Deng, Edison, NJ (US);
Zhijian LU, Clinton, NJ (US);
Peter J. Sinclair, Doylestown, PA (US);
Gayle E. Hallett, Smethwick, GB;
Christopher F. Thompson, Arlington, MA (US);
Nazia Quraishi, Bethesda, MD (US);
Cameron J. Smith, Lawrenceville, NJ (US);
Amjad Ali, Freehold, NJ (US);
Joann M. Napolitano, North Plainfield, NJ (US);
Qiaolin Deng, Edison, NJ (US);
Zhijian Lu, Clinton, NJ (US);
Peter J. Sinclair, Doylestown, PA (US);
Gayle E. Hallett, Smethwick, GB;
Christopher F. Thompson, Arlington, MA (US);
Nazia Quraishi, Bethesda, MD (US);
Cameron J. Smith, Lawrenceville, NJ (US);
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Abstract
Compounds having the structures of Formula I, including pharmaceutically acceptable salts of the compounds, are CETP inhibitors, and are useful for raising HDL-cholesterol, reducing LDL-cholesterol, and for treating or preventing atherosclerosis: In the compounds of Formula I, B or Ris a phenyl group which has an ortho aryl, heterocyclic, benzoheterocyclic or benzocycloalkyl substituent, and one other position on the 5-membered ring has an aromatic, heterocyclic, cycloalkyl, benzoheterocyclic or benzocycloalkyl substituent connected directly to the ring or attached to the ring through a —CH—.