The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 27, 2014
Filed:
Jul. 02, 2009
Dieter Kadereit, Frankfurt am Main, DE;
Matthias Schaefer, Frankfurt am Main, DE;
Werngard Czechtizky, Frankfurt am Main, DE;
Dieter Kadereit, Frankfurt am Main, DE;
Matthias Schaefer, Frankfurt am Main, DE;
Werngard Czechtizky, Frankfurt am Main, DE;
Sanofi, Paris, FR;
Abstract
The present invention relates to oxazolopyrimidine compounds of the formula I in which A, R, Rand Rare defined as indicated in the claims. The compounds of the formula I modulate the activity of the Edg-1 receptor and in particular are agonists of this receptor, and are useful for the treatment of diseases such as atherosclerosis, heart failure or peripheral arterial occlusive disease, for example. The invention furthermore relates to processes for the preparation of compounds of the formula I, their use, in particular as active ingredients in pharmaceuticals, and pharmaceutical compositions comprising them.