The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 27, 2014
Filed:
Aug. 22, 2011
Young-tae Chang, Singapore, SG;
Hyung Ho Ha, Singapore, SG;
Nam Young Kang, Singapore, SG;
Seong Wook Yun, Singapore, SG;
Sung Jin Park, Singapore, SG;
Young-hoon Ahn, Baltimore, MD (US);
Young-Tae Chang, Singapore, SG;
Hyung Ho Ha, Singapore, SG;
Nam Young Kang, Singapore, SG;
Seong Wook Yun, Singapore, SG;
Sung Jin Park, Singapore, SG;
Young-Hoon Ahn, Baltimore, MD (US);
New York University, New York, NY (US);
National University of Singapore, Singapore, SG;
Agency for Science, Technology & Research, Singapore, SG;
Abstract
The present invention relates to methods of detecting, in a sample, embryonic stem cells, induced pluripotent stem cells, and/or cells undergoing reprogramming to produce induced pluripotent stem cells. These methods include providing a sample potentially containing such cells and providing a rosamine derivative compound of the formula (I): where the rosamine derivative compound selectively produces fluorescent signals for embryonic stem cells, induced pluripotent stem cells, and/or cells undergoing reprogramming to produce induced pluripotent stem cells. These methods also include the steps of contacting the sample with the rosamine derivative compound and detecting the presence of the embryonic stem cells, induced pluripotent stem cells, and/or cells undergoing reprogramming to produce induced pluripotent stem cells based on fluorescent signals emitted by the sample following said contacting.