The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 27, 2014
Filed:
Apr. 05, 2009
Benjamin Reubinoff, Doar Na Haela, IL;
Etti Ben Shushan, Jerusalem, IL;
Michal Aharonowiz, Modiin, IL;
Benjamin Reubinoff, Doar Na Haela, IL;
Etti Ben Shushan, Jerusalem, IL;
Michal Aharonowiz, Modiin, IL;
Hadasit Medical Research Services & Development Limited, Jerusalem, IL;
Abstract
Provided is a method for directing differentiation of neural progenitors with a caudal and ventral specification into motor neurons including culturing neural progenitors in a culturing medium including a basic medium supplemented by at least one inhibitor of the Notch signaling pathway whereby the neural progenitors differentiate into postmitotic motor neurons. The resulting motor neurons may be used for drug development, as carriers, e.g. for gene therapy of protein delivery as well as for transplantation for the purpose of treating a motor neuron disease.