The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 27, 2014
Filed:
Jun. 29, 2012
Katalin Varadi, Vienna, AT;
Peter Turecek, Klosterneuburg, AT;
Brigitte Keil, Vienna, AT;
Sylvia Peyrer-heimstaett, Vienna, AT;
Hans-peter Schwarz, Vienna, AT;
Katalin Varadi, Vienna, AT;
Peter Turecek, Klosterneuburg, AT;
Brigitte Keil, Vienna, AT;
Sylvia Peyrer-Heimstaett, Vienna, AT;
Hans-Peter Schwarz, Vienna, AT;
Baxter International Inc., Dearfield, IL (US);
Baxter Healthcare SA, Glattpark (Opfikon), CH;
Abstract
The invention provides a kit for measuring the thrombin generation in a sample of a patient's blood or plasma, or in a sample of clotting factors. The kit contains lyophilized tissue factor/phospholipid-complex and a lyophilized mixture containing a thrombin-substrate and CaCl. The invention also provides processes for preparing the reagents for the kit. The kit can be used in a method for measuring the thrombin generation in a sample, wherein it is possible to detect changes in thrombin generation kinetics, for example after administration of inhibitor bypassing agents to a patient who has developed inhibitors to an exogenous clotting factor such as Factor VIII.