The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 27, 2014

Filed:

May. 01, 2006
Applicants:

David M. Lynn, Middleton, WI (US);

Jingtao Zhang, Madison, WI (US);

Christopher M. Jewell, Madison, WI (US);

Nathaniel J. Fredin, Madison, WI (US);

Inventors:

David M. Lynn, Middleton, WI (US);

Jingtao Zhang, Madison, WI (US);

Christopher M. Jewell, Madison, WI (US);

Nathaniel J. Fredin, Madison, WI (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/16 (2006.01); A61K 9/14 (2006.01); A61K 47/44 (2006.01); C12Q 1/68 (2006.01); C12N 15/00 (2006.01); C12N 15/88 (2006.01); C12N 15/87 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides implantable medical devices coated with polyelectrolyte assemblies that are fabricated by layer-by-layer deposition of nucleic acid and polycation. Such devices facilitate the local delivery of a nucleic acid contained in the polyelectrolyte assembly into a cell or tissue at an implantation site. Also provided are methods of fabricating and using implantable medical devices according to the invention.


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