The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 27, 2014

Filed:

Jul. 15, 2004
Applicants:

Rosario Lízio, Rossdorf, DE;

Hans-ulrich Petereit, Darmstadt, DE;

Erna Roth, Darmstadt, DE;

Inès Andres, Varese, IT;

Michael Damm, Rödermark, DE;

Inventors:

Rosario Lízio, Rossdorf, DE;

Hans-Ulrich Petereit, Darmstadt, DE;

Erna Roth, Darmstadt, DE;

Inès Andres, Varese, IT;

Michael Damm, Rödermark, DE;

Assignee:

Evonik Roehm GmbH, Darmstadt, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/14 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention relates to an oral, multiparticle pharmaceutical dosage form containing pellets, the size of which ranges from 50 to 2500 μm and which essentially consist of: a) an inner matrix layer containing an active substance which is a peptide or a protein, including the derivatives or conjugates thereof, and which is embedded in a matrix consisting of a polymer with mucoadhesive effect, and b) an outer film coating essentially consisting of an anionic polymer or copolymer, which can be optionally formulated with pharmaceutically conventional adjuvants, more particularly softening agents.


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