The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 27, 2014

Filed:

Aug. 04, 2008
Applicants:

Mark Heffernan, Dublin, IE;

Luke O'neill, Dublin, IE;

Peter Mcguirk, Dublin, IE;

Brian Keogh, Dublin, IE;

Christopher Locher, Lexington, MA (US);

Dominique DE Kleijn, Utrecht, NL;

Fatih Arslan, Utrecht, NL;

Gerard Pasterkamp, Utrecht, NL;

Inventors:

Mark Heffernan, Dublin, IE;

Luke O'Neill, Dublin, IE;

Peter McGuirk, Dublin, IE;

Brian Keogh, Dublin, IE;

Christopher Locher, Lexington, MA (US);

Dominique De Kleijn, Utrecht, NL;

Fatih Arslan, Utrecht, NL;

Gerard Pasterkamp, Utrecht, NL;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C07K 16/28 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/3955 (2013.01); C07K 16/28 (2013.01); C07K 16/2803 (2013.01); C07K 16/2896 (2013.01); A61K 2039/505 (2013.01); C07K 2316/96 (2013.01); C07K 2317/76 (2013.01);
Abstract

The present invention provides compounds and methods for the treatment and prophylaxis of ischemia reperfusion injury. In particular the invention provides compounds which function to suppress Toll-like Receptor 2 biological function or expression.


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