The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 27, 2014
Filed:
Nov. 28, 2012
Applicant:
Zymogenetics, Inc., Princeton, NJ (US);
Inventors:
Lowell J. Brady, Tacoma, WA (US);
Kevin M. Klucher, Bellevue, WA (US);
Chung Chan, Sammamish, WA (US);
Dennis L. Dong, Berwyn, PA (US);
Hong Y. Liu, Beijing, CN;
Paul O. Sheppard, Granite Falls, WA (US);
Thomas R. Bukowski, Seattle, WA (US);
Assignee:
ZymoGenetics, Inc., Seattle, WA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/19 (2006.01); C07K 14/54 (2006.01); A61K 45/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
Homogeneous preparations of IL-28A, IL-28B, and IL-29 have been produced by mutating one or more of the cysteine residues in the polynucleotide sequences encoding the mature proteins. The cysteine mutant proteins can be shown to either bind to their cognate receptor or exhibit biological activity. One type of biological activity that is shown is an antiviral activity.