The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 27, 2014
Filed:
Aug. 26, 2011
Cecelia C. Yates-binder, Pittsburgh, PA (US);
Jesse Jaynes, Auburn, AL (US);
Timothy Turner, Auburn, AL (US);
Alan Wells, Pittsburgh, PA (US);
Richard J. Bodnar, Pittsburgh, PA (US);
Cecelia C. Yates-Binder, Pittsburgh, PA (US);
Jesse Jaynes, Auburn, AL (US);
Timothy Turner, Auburn, AL (US);
Alan Wells, Pittsburgh, PA (US);
Richard J. Bodnar, Pittsburgh, PA (US);
University of Pittsburgh, Pittsburgh, PA (US);
Tuskegee University, Tuskegee, AL (US);
Abstract
Disclosed are peptides having activity against receptor CXCR3 are disclosed that exhibit activity in preventing the formation of new vessels and activity in mediating the dissociation of newly-formed vessels and resolving of wounds in the later stages of wound healing. Preferred peptides are derived from the α-helix portion IP-10 (CXCL10) or from IP-9 (CXCL11), are nontoxic, and smaller than naturally occurring peptides, making them useful in therapies against diseases or disease states marked by unwanted angiogenesis, including tumorogenic diseases such as cancers, and in healing of chronic wounds.