The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 20, 2014
Filed:
Oct. 21, 2011
David Klotzkin, Vestal, NY (US);
David Klotzkin, Vestal, NY (US);
The Research Foundation for The State University of New York, Binghamton, NY (US);
Abstract
Microfluidics has made great progress in integrating many aspects of biological analysis and testing into the microscale. One aspect which has proven challenging to miniaturize has been fluorescence testing, as a complete fluorescence system requires an integrated light source, detector and filters to filter out the excitation light (from the light source) from the detector. Here we demonstrate that with polarization filtering of the excitation light and multiple dye sources modulated at different frequencies, a high-sensitivity, multi-dye system with one detector can be realized. Simultaneous detection and quantition of a mixture of two different dyes is demonstrated with no physical change in the measurement setup. The degree of interaction of the dyes is measured. This system is readily adaptable to integrated lab-on-a-chip microfluorescence.