The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 20, 2014

Filed:

Aug. 15, 2011
Applicants:

Linas Kudzma, Annandale, NJ (US);

Ronald Bell, Glen Gardner, NJ (US);

Yongxian Zeng, Edison, NJ (US);

Leonid A. Rozov, Fair Lawn, NJ (US);

Inventors:

Linas Kudzma, Annandale, NJ (US);

Ronald Bell, Glen Gardner, NJ (US);

Yongxian Zeng, Edison, NJ (US);

Leonid A. Rozov, Fair Lawn, NJ (US);

Assignees:

Baxter International Inc., Deerfield, IL (US);

Baxter Healthcare SA, Glattpark (Opfikon), CH;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 41/22 (2006.01); C07C 41/38 (2006.01); C07C 41/42 (2006.01); C07C 43/12 (2006.01);
U.S. Cl.
CPC ...
C07C 41/22 (2013.01); C07C 41/38 (2013.01); C07C 41/42 (2013.01); C07C 43/123 (2013.01);
Abstract

The present invention provides a method for forming sevoflurane comprising (i) combining chlorosevo ether, a nucleophilic fluoride reagent, and a solvent comprising sevoflurane to form an initial reaction mixture and (ii) reacting the initial reaction mixture to form additional sevoflurane relative to the amount of sevoflurane present in the initial reaction mixture. The present disclosure is also directed to a method for forming sevoflurane, comprising: initiating a reaction between chlorosevo ether and a nucleophilic fluoride reagent in an initial reaction mixture further comprising a solvent comprising sevoflurane, thereby forming additional sevoflurane relative to the amount of sevoflurane present in the initial reaction mixture.


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